Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease
Hepatitis C virus (HCV) non-structural protein 2 (NS2) encodes an autoprotease activity that is essential for virus replication and thus represents an attractive anti-viral target. Recently, we demonstrated that a series of epoxide-based compounds, previously identified as potent inhibitors of the c...
Main Authors: | Shaw, Joseph, Harris, Mark, Fishwick, Colin W.G. |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678293/ |
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