Analysis of T cell responses to chimpanzee adenovirus vectors encoding HIV gag–pol–nef antigen

Adenoviruses have been shown to be both immunogenic and efficient at presenting HIV proteins but recent trials have suggested that they may play a role in increasing the risk of HIV acquisition. This risk may be associated with the presence of pre-existing immunity to the viral vectors. Chimpanzee a...

Full description

Bibliographic Details
Main Authors: Herath, S., Le Heron, A., Colloca, S., Bergin, P., Patterson, S., Weber, J., Tatoud, R., Dickson, G.
Format: Online
Language:English
Published: Elsevier Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678176/