Isochromosome 17q in Chronic Lymphocytic Leukemia

In chronic lymphocytic leukemia (CLL), presence of acquired cytogenetic abnormalities may help to estimate prognosis. However, deletion of TP53 gene, which is associated with an aggressive course of the disease and poor prognosis along with a lack of response to treatment, is one of the alterations...

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Bibliographic Details
Main Authors: Alhourani, Eyad, Rincic, Martina, Melo, Joana B., Carreira, Isabel M., Glaser, Anita, Pohle, Beate, Schlie, Cordula, Liehr, Thomas
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677221/