Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney

The transcription factor Nrf2 exerts protective effects in numerous experimental models of acute kidney injury, and is a promising therapeutic target in chronic kidney disease. To provide a detailed insight into the regulatory roles of Nrf2 in the kidney, we performed integrated transcriptomic and p...

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Bibliographic Details
Main Authors: Shelton, Luke M., Lister, Adam, Walsh, Joanne, Jenkins, Rosalind E., Wong, Michael H. L., Rowe, Cliff, Ricci, Emanuele, Ressel, Lorenzo, Fang, Yongxiang, Demougin, Philippe, Vukojevic, Vanja, O’Neill, Paul M., Goldring, Christopher E., Kitteringham, Neil R., Park, B. Kevin, Odermatt, Alex, Copple, Ian M.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676083/