Metformin prevents DMH-induced colorectal cancer in diabetic rats by reversing the warburg effect

Epidemiologic studies have shown that the treatment of diabetics with metformin reduced the risk of cancer-related mortality. Here, we investigated the chemopreventive effects of metformin on dimethylhydrazine (DMH)-induced colorectal carcinogenesis in diabetic SD rats following metformin treatment...

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Bibliographic Details
Main Authors: Jia, Yanglei, Ma, Zengyi, Liu, Xiaofei, Zhou, Wenjing, He, Shan, Xu, Xia, Ren, Guijie, Xu, Gang, Tian, Keli
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674000/