TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Despite its importance during viral or bacterial infections, transcriptional regulation of the interferon-β gene (Ifnb1) in activated macrophages is only partially understood. Here we report that TRIM33 deficiency results in high, sustained expression of Ifnb1 at late stages of toll-like receptor-me...

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Bibliographic Details
Main Authors: Ferri, Federica, Parcelier, Aude, Petit, Vanessa, Gallouet, Anne-Sophie, Lewandowski, Daniel, Dalloz, Marion, van den Heuvel, Anita, Kolovos, Petros, Soler, Eric, Squadrito, Mario Leonardo, De Palma, Michele, Davidson, Irwin, Rousselet, Germain, Romeo, Paul-Henri
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673826/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673826/

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