Contraction stimulates muscle glucose uptake independent of atypical PKC

Exercise increases skeletal muscle glucose uptake, but the underlying mechanisms are only partially understood. The atypical protein kinase C (PKC) isoforms λ and ζ (PKC‐λ/ζ) have been shown to be necessary for insulin‐, AICAR‐, and metformin‐stimulated glucose uptake in skeletal muscle, but not for...

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Bibliographic Details
Main Authors: Yu, Haiyan, Fujii, Nobuharu L., Toyoda, Taro, An, Ding, Farese, Robert V., Leitges, Michael, Hirshman, Michael F., Mul, Joram D., Goodyear, Laurie J.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673624/