Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity

Tumor cells able to recapitulate tumor heterogeneity have been tracked, isolated and characterized in different tumor types, and are commonly named Cancer Stem Cells or Cancer Initiating Cells (CSC/CIC). CSC/CIC are disseminated in the tumor mass and are resistant to anti-cancer therapies and advers...

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Bibliographic Details
Main Authors: Albini, Adriana, Bruno, Antonino, Gallo, Cristina, Pajardi, Giorgio, Noonan, Douglas M., Dallaglio, Katiuscia
Format: Online
Language:English
Published: Informa Healthcare 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673538/