Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies

Optimal animal models of muscle invasive bladder cancer (MIBC) are necessary to overcome the current lack of novel targeted therapies for this malignancy. Here we report on the establishment and characterization of patient-derived primary xenografts (PDX). Patient tumors were grafted under the renal...

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Bibliographic Details
Main Authors: Jäger, Wolfgang, Xue, Hui, Hayashi, Tetsutaro, Janssen, Claudia, Awrey, Shannon, Wyatt, Alexander W., Anderson, Shawn, Moskalev, Igor, Haegert, Anne, Alshalalfa, Mohammed, Erho, Nicholas, Davicioni, Elai, Fazli, Ladan, Li, Estelle, Collins, Colin, Wang, Yuzhuo, Black, Peter C.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673283/