Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice

Immunosenescence contributes to pathogenesis of Alzheimer's disease (AD) in the elderly. In this study, we explored the effects of young wild type (WT) splenocytes (ySCs) on Alzheimer's disease by transplanting ySCs into APPswe/PSENldE9 transgenic mice. Young WT splenocytes not only preven...

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Bibliographic Details
Main Authors: Wang, Fei, Shen, Xueyan, Li, Shuping, Chen, Long, Wang, Yanru, Qin, Jie, Zhou, Guomin, Peng, Yuwen, Feng, Xiaoyuan, Li, Ruixi, Liang, Chunmin
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673234/