MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis

Growth and invasion of metastatic colorectal cancer (CRC) cells in the liver depend on microenvironment. Here, we showed that human hepatic sinusoidal endothelial cells (HHSECs) induce chemotaxis and outgrowth of CRC cells. Macrophage migration inhibitory factor (MIF), released by HHSECs, stimulated...

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Bibliographic Details
Main Authors: Hu, Chun-Ting, Guo, Li-Li, Feng, Na, Zhang, Lei, Zhou, Na, Ma, Li-Li, Shen, Lan, Tong, Gui-Hui, Yan, Qian-Wen, Zhu, Shi-Jie, Bian, Xiu-Wu, Lai, Mao-De, Deng, Yong-Jian, Ding, Yan-Qing
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673172/