Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

Withanolide E, a steroidal lactone from Physalis peruviana, was found to be highly active for sensitizing renal carcinoma cells and a number of other human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis. Withanolide E, the most potent and least tox...

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Bibliographic Details
Main Authors: Henrich, C J, Brooks, A D, Erickson, K L, Thomas, C L, Bokesch, H R, Tewary, P, Thompson, C R, Pompei, R J, Gustafson, K R, McMahon, J B, Sayers, T J
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669816/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669816/

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