The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses

Adeno-associated viruses are members of the genus dependoviruses of the parvoviridae family. AAV vectors are considered promising vectors for gene therapy and genetic vaccination as they can be easily produced, are highly stable and non-pathogenic. Nevertheless, transduction of cells in vitro and in...

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Bibliographic Details
Main Authors: Hölscher, Christina, Sonntag, Florian, Henrich, Katharina, Chen, Qingxin, Beneke, Jürgen, Matula, Petr, Rohr, Karl, Kaderali, Lars, Beil, Nina, Erfle, Holger, Kleinschmidt, Jürgen A., Müller, Martin
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666624/