Detecting Differentially Expressed Genes with RNA-seq Data Using Backward Selection to Account for the Effects of Relevant Covariates
A common challenge in analysis of transcriptomic data is to identify differentially expressed genes, i.e., genes whose mean transcript abundance levels differ across the levels of a factor of scientific interest. Transcript abundance levels can be measured simultaneously for thousands of genes in mu...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666287/ |