In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa

The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required. In order to identify new candidates as potential drug targets, we combined large-scale transposon mutagenesis data anal...

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Bibliographic Details
Main Authors: Fernández-Piñar, Regina, Lo Sciuto, Alessandra, Rossi, Alice, Ranucci, Serena, Bragonzi, Alessandra, Imperi, Francesco
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665194/