Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

The histone variant H2A.Z is a hallmark of nucleosomes flanking promoters of protein-coding genes and is often found in nucleosomes that carry lysine 56-acetylated histone H3 (H3-K56Ac), a mark that promotes replication-independent nucleosome turnover. Here, we find that H3-K56Ac promotes RNA polyme...

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Bibliographic Details
Main Authors: Rege, Mayuri, Subramanian, Vidya, Zhu, Chenchen, Hsieh, Tsung-Han S., Weiner, Assaf, Friedman, Nir, Clauder-Münster, Sandra, Steinmetz, Lars M., Rando, Oliver J., Boyer, Laurie A., Peterson, Craig L.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662874/