MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone

MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone

Giant cell tumor (GCT) of bone consists of three major cell types: giant cells, monocytic cells, and stromal cells. From microarray analysis, we found that miR-106b was down-regulated in GCT clinical samples and further determined by fluorescence in situ hybridization. In addition, the expression of...

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Bibliographic Details
Main Authors: Wang, Ting, Yin, Huabin, Wang, Jing, Li, Zhenxi, Wei, Haifeng, Liu, Zhi'an, Wu, Zhipeng, Yan, Wangjun, Liu, Tielong, Song, Dianwen, Yang, Xinghai, Huang, Quan, Zhou, Wang, Xiao, Jianru
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662469/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662469/

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