Parvalbumin-positive interneurons of the prefrontal cortex support working memory and cognitive flexibility

Dysfunction of parvalbumin (PV)-positive GABAergic interneurons (PVIs) within the prefrontal cortex (PFC) has been implicated in schizophrenia pathology. It is however unclear, how impaired signaling of these neurons may contribute to PFC dysfunction. To identify how PVIs contribute to PFC-dependent...

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Bibliographic Details
Main Authors: Murray, Andrew J., Woloszynowska-Fraser, Marta U., Ansel-Bollepalli, Laura, Cole, Katy L. H., Foggetti, Angelica, Crouch, Barry, Riedel, Gernot, Wulff, Peer
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660359/