Single-molecule visualization of a formin-capping protein ‘decision complex' at the actin filament barbed end

Precise control of actin filament length is essential to many cellular processes. Formins processively elongate filaments, whereas capping protein (CP) binds to barbed ends and arrests polymerization. While genetic and biochemical evidence has indicated that these two proteins function antagonistica...

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Bibliographic Details
Main Authors: Bombardier, Jeffrey P., Eskin, Julian A., Jaiswal, Richa, Corrêa, Ivan R., Xu, Ming-Qun, Goode, Bruce L., Gelles, Jeff
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660045/