Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes

Interleukin (IL)-15 has multiple roles in innate and adaptive immunity, especially regarding CD8+ T cells and natural killer cells. However, the role of IL-15 in regulating differentiation of T helper cell subsets and mononuclear phagocytes (MPs) in different tissues in vivo is unknown. Here we repo...

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Bibliographic Details
Main Authors: Yu, Huifeng, Sui, Yongjun, Wang, Yichuan, Sato, Noriko, Frey, Blake, Xia, Zheng, Waldmann, Thomas A., Berzofsky, Jay
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658142/