The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration
The control of proliferation and differentiation by tumor suppressor genes suggests that evolution of divergent tumor suppressor repertoires could influence species’ regenerative capacity. To directly test that premise, we humanized the zebrafish p53 pathway by introducing regulatory and coding sequ...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657621/ |