TDP-43 is intercellularly transmitted across axon terminals

TDP-43 is intercellularly transmitted across axon terminals

A protein complementation assay quantifying TDP-43 oligomerization in living neurons shows microvesicular and bidirectional synaptic transmission of TDP-43 and TDP-43 seeding activity in human ALS postmortem brain tissue.

Bibliographic Details
Main Authors: Feiler, Marisa S., Strobel, Benjamin, Freischmidt, Axel, Helferich, Anika M., Kappel, Julia, Brewer, Bryson M., Li, Deyu, Thal, Dietmar R., Walther, Paul, Ludolph, Albert C., Danzer, Karin M., Weishaupt, Jochen H.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657165/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657165/

Similar Items