The Triterpenoid Betulin Protects against the Neuromuscular Effects of Bothrops jararacussu Snake Venom In Vivo

We confirmed the ability of the triterpenoid betulin to protect against neurotoxicity caused by Bothrops jararacussu snake venom in vitro in mouse isolated phrenic nerve-diaphragm (PND) preparations and examined its capability of in vivo protection using the rat external popliteal/sciatic nerve-tibi...

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Bibliographic Details
Main Authors: Ferraz, Miriéle Cristina, de Oliveira, Jhones Luiz, de Oliveira Junior, Joel Reis, Cogo, José Carlos, dos Santos, Márcio Galdino, Franco, Luiz Madaleno, Puebla, Pilar, Ferraz, Helena Onishi, Ferraz, Humberto Gomes, da Rocha, Marisa Maria Teixeira, Hyslop, Stephen, San Feliciano, Arturo, Oshima-Franco, Yoko
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655057/