Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

The functional dynamics and cellular sources of oxidative stress are central to understanding MS pathogenesis but remain elusive, due to the lack of appropriate detection methods. Here we employ NAD(P)H fluorescence lifetime imaging to detect functional NADPH oxidases (NOX enzymes) in vivo to identi...

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Bibliographic Details
Main Authors: Mossakowski, Agata A., Pohlan, Julian, Bremer, Daniel, Lindquist, Randall, Millward, Jason M., Bock, Markus, Pollok, Karolin, Mothes, Ronja, Viohl, Leonard, Radbruch, Moritz, Gerhard, Jenny, Bellmann-Strobl, Judith, Behrens, Janina, Infante-Duarte, Carmen, Mähler, Anja, Boschmann, Michael, Rinnenthal, Jan Leo, Füchtemeier, Martina, Herz, Josephine, Pache, Florence C., Bardua, Markus, Priller, Josef, Hauser, Anja E., Paul, Friedemann, Niesner, Raluca, Radbruch, Helena
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654749/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654749/

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