Hepatitis B virus spliced variants are associated with an impaired response to interferon therapy

During hepatitis B virus (HBV) replication, spliced HBV genomes and splice-generated proteins have been widely described, however, their biological and clinical significance remains to be defined. Here, an elevation of the proportion of HBV spliced variants in the sera of patients with chronic hepat...

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Bibliographic Details
Main Authors: Chen, Jieliang, Wu, Min, Wang, Fan, Zhang, Wen, Wang, Wei, Zhang, Xiaonan, Zhang, Jiming, Liu, Yinghui, Liu, Yi, Feng, Yanling, Zheng, Ye, Hu, Yunwen, Yuan, Zhenghong
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653653/