Molecular portraits: the evolution of the concept of transcriptome-based cancer signatures

Cancer results from dysregulation of multiple steps of gene expression programs. We review how transcriptome profiling has been widely explored for cancer classification and biomarker discovery but resulted in limited clinical impact. Therefore, we discuss alternative and complementary omics approac...

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Bibliographic Details
Main Authors: Modelska, Angelika, Quattrone, Alessandro, Re, Angela
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652618/