Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes

MHC α-helices form the antigen-binding cleft and are of particular interest for immunological reactions. To monitor these helices in molecular dynamics simulations, we applied a parsimonious fragment-fitting method to trace the axes of the α-helices. Each resulting axis was fitted by polynomials in...

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Bibliographic Details
Main Authors: Ribarics, Reiner, Kenn, Michael, Karch, Rudolf, Ilieva, Nevena, Schreiner, Wolfgang
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651647/