Optogenetic induction of contractile ability in immature C2C12 myotubes

Myoblasts can be differentiated into multinucleated myotubes, which provide a well-established and reproducible muscle cell model for skeletal myogenesis in vitro. However, under conventional differentiation conditions, each myotube rarely exhibits robust contraction as well as sarcomere arrangement...

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Bibliographic Details
Main Authors: Asano, Toshifumi, Ishizuka, Toru, Morishima, Keisuke, Yawo, Hiromu
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650824/