Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin

The Sall2 transcription factor is deregulated in several cancers; however, little is known about its cellular functions, including its target genes. Recently, we demonstrated that p53 directly regulates Sall2 expression under genotoxic stress. Here, we investigated the role of Sall2 in the context o...

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Bibliographic Details
Main Authors: Escobar, D, Hepp, M I, Farkas, C, Campos, T, Sodir, N M, Morales, M, Álvarez, C I, Swigart, L, Evan, G I, Gutiérrez, J L, Nishinakamura, R, Castro, A F, Pincheira, R
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650718/