MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer

MAP3K3 is involved in both the immune response and in tumor progression. Its potential biological role in vitro in lung cancer cell lines and the association of mRNA/protein expression patterns with clinical outcome of primary lung tumors were investigated in this study. Silencing MAP3K3 using siRNA...

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Bibliographic Details
Main Authors: He, Yanli, Wang, Lihui, Liu, Weijun, Zhong, Jinjie, Bai, Shengbin, Wang, Zhuwen, Thomas, Dafydd G., Lin, Jules, Reddy, Rishindra M., Ramnath, Nithya, Carrott, Philip W., Lynch, William R., Orringer, Mark B., Chang, Andrew C., Beer, David G., Chen, Guoan
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650617/