Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation

Peroxisome proliferator-activated receptors (PPARs) participate in energy homeostasis and play essential roles in diabetes therapy through their effects on non-pancreas tissues. Pathological microenvironment may influence the metabolic requirements for the maintenance of stem cell differentiation. A...

Full description

Bibliographic Details
Main Authors: Li, L, Li, T, Zhang, Y, Pan, Z, Wu, B, Huang, X, Mei, Y, Ge, L, Shen, G, Ge, R-s, Zhu, D, Lou, Y
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650555/