A novel antagonist to the inhibitors of apoptosis (IAPs) potentiates cell death in EGFR-overexpressing non-small-cell lung cancer cells

A novel antagonist to the inhibitors of apoptosis (IAPs) potentiates cell death in EGFR-overexpressing non-small-cell lung cancer cells

In the effort to develop an efficient chemotherapy drug for the treatment of non-small-cell lung cancer (NSCLC), we analyzed the anti-tumorigenic effects of a novel small molecule targeting the inhibitor of apoptosis (IAPs), HM90822B, on NSCLC cells. HM90822B efficiently decreased IAP expression, es...

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Bibliographic Details
Main Authors: Lee, S-H, Lee, J-Y, Jung, C L, Bae, I H, Suh, K H, Ahn, Y G, Jin, D-H, Kim, T W, Suh, Y-A, Jang, S J
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649530/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649530/

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