Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases
Interleukin (IL)-15 is a dangerous inflammatory cytokine that induces tumor-necrosis factor-α, IL-1β and inflammatory chemokines. It inhibits self-tolerance mediated by IL-2 mediated activation-induced cell death and facilitates maintenance of CD8+ memory T-cell survival including that of self-direc...
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| Format: | Online |
| Language: | English |
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BioMed Central
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC464917/ |