Inferring the Clonal Structure of Viral Populations from Time Series Sequencing

RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We would like to identify the underlying evolutionary structures....

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Bibliographic Details
Main Authors: Chedom, Donatien F., Murcia, Pablo R., Greenman, Chris D.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646700/