Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in Cells*

Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in Cells*

Background: α-Synuclein aggregation is associated with Parkinson disease.

Bibliographic Details
Main Authors: Moree, Ben, Yin, Guowei, Lázaro, Diana F., Munari, Francesca, Strohäker, Timo, Giller, Karin, Becker, Stefan, Outeiro, Tiago F., Zweckstetter, Markus, Salafsky, Joshua
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646010/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646010/

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