Dzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation

Dzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation

In mouse embryonic stem (mES) cells, ubiquitylation of histone H2A lysine 119 represses a large number of developmental genes and maintains mES cell pluripotency. It has been suggested that a number of H2A ubiquitin ligases as well as deubiquitylases and related peptide fragments contribute to a del...

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Bibliographic Details
Main Authors: Inoue, Daishi, Aihara, Hitoshi, Sato, Tatsuharu, Mizusaki, Hirofumi, Doiguchi, Masamichi, Higashi, Miki, Imamura, Yuko, Yoneda, Mitsuhiro, Miyanishi, Takayuki, Fujii, Satoshi, Okuda, Akihiko, Nakagawa, Takeya, Ito, Takashi
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645096/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645096/

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