Spaceflight Effects on Cytochrome P450 Content in Mouse Liver

Hard conditions of long-term manned spaceflight can affect functions of many biological systems including a system of drug metabolism. The cytochrome P450 (CYP) superfamily plays a key role in the drug metabolism. In this study we examined the hepatic content of some P450 isoforms in mice exposed to...

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Bibliographic Details
Main Authors: Moskaleva, Natalia, Moysa, Alexander, Novikova, Svetlana, Tikhonova, Olga, Zgoda, Victor, Archakov, Alexander
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641588/