Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo

Duchenne muscular dystrophy (DMD) is a fatal disease of striated muscle deterioration. A unique therapeutic approach for DMD is the use of synthetic membrane stabilizers to protect the fragile dystrophic sarcolemma against contraction-induced mechanical stress. Block copolymer-based membrane stabili...

Full description

Bibliographic Details
Main Authors: Houang, Evelyne M, Haman, Karen J, Filareto, Antonio, Perlingeiro, Rita C, Bates, Frank S, Lowe, Dawn A, Metzger, Joseph M
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641511/