Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?

A number of studies have shown that non-invasive brain stimulation has an additional effect in combination with rehabilitative therapy to enhance functional recovery than either therapy alone. The combination enhances use-dependent plasticity induced by repetitive training. The neurophysiological me...

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Main Authors:	Koganemaru, Satoko, Fukuyama, Hidenao, Mima, Tatsuya
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639697/

id	pubmed-4639697
recordtype	oai_dc
spelling	pubmed-46396972015-11-27 Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery? Koganemaru, Satoko Fukuyama, Hidenao Mima, Tatsuya Neuroscience A number of studies have shown that non-invasive brain stimulation has an additional effect in combination with rehabilitative therapy to enhance functional recovery than either therapy alone. The combination enhances use-dependent plasticity induced by repetitive training. The neurophysiological mechanism of the effects of this combination is based on associative plasticity. However, these effects were not reported in all cases. We propose a list of possible strategies to achieve an effective association between rehabilitative training with brain stimulation for plasticity: (1) control of temporal aspect between stimulation and task execution; (2) the use of a shaped task for the combination; (3) the appropriate stimulation of neuronal circuits where use-dependent plastic changes occur; and (4) phase synchronization between rhythmically patterned brain stimulation and task-related patterned activities of neurons. To better utilize brain stimulation in neuro-rehabilitation, it is important to develop more effective techniques to combine them. Frontiers Media S.A. 2015-11-10 /pmc/articles/PMC4639697/ /pubmed/26617497 http://dx.doi.org/10.3389/fnsys.2015.00154 Text en Copyright © 2015 Koganemaru, Fukuyama and Mima. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Koganemaru, Satoko Fukuyama, Hidenao Mima, Tatsuya
spellingShingle	Koganemaru, Satoko Fukuyama, Hidenao Mima, Tatsuya Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
author_facet	Koganemaru, Satoko Fukuyama, Hidenao Mima, Tatsuya
author_sort	Koganemaru, Satoko
title	Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
title_short	Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
title_full	Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
title_fullStr	Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
title_full_unstemmed	Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?
title_sort	two is more than one: how to combine brain stimulation rehabilitative training for functional recovery?
description	A number of studies have shown that non-invasive brain stimulation has an additional effect in combination with rehabilitative therapy to enhance functional recovery than either therapy alone. The combination enhances use-dependent plasticity induced by repetitive training. The neurophysiological mechanism of the effects of this combination is based on associative plasticity. However, these effects were not reported in all cases. We propose a list of possible strategies to achieve an effective association between rehabilitative training with brain stimulation for plasticity: (1) control of temporal aspect between stimulation and task execution; (2) the use of a shaped task for the combination; (3) the appropriate stimulation of neuronal circuits where use-dependent plastic changes occur; and (4) phase synchronization between rhythmically patterned brain stimulation and task-related patterned activities of neurons. To better utilize brain stimulation in neuro-rehabilitation, it is important to develop more effective techniques to combine them.
publisher	Frontiers Media S.A.
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639697/
_version_	1613499366504398848

Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery?

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