Identifying robust communities and multi-community nodes by combining top-down and bottom-up approaches to clustering

Biological functions are carried out by groups of interacting molecules, cells or tissues, known as communities. Membership in these communities may overlap when biological components are involved in multiple functions. However, traditional clustering methods detect non-overlapping communities. Thes...

Full description

Bibliographic Details
Main Authors: Gaiteri, Chris, Chen, Mingming, Szymanski, Boleslaw, Kuzmin, Konstantin, Xie, Jierui, Lee, Changkyu, Blanche, Timothy, Chaibub Neto, Elias, Huang, Su-Chun, Grabowski, Thomas, Madhyastha, Tara, Komashko, Vitalina
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637843/