BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy

BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy

Here, we found that BTG1 overexpression inhibited proliferation, migration and invasion, induced G2/M arrest, differentiation, senescence and apoptosis in BGC-823 and MKN28 cells (p < 0.05). BTG1 transfectants showed a higher mRNA expression of Cyclin D1 and Bax, but a lower mRNA expression of cd...

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Bibliographic Details
Main Authors: Zheng, Hua-chuan, Li, Jing, Shen, Dao-fu, Yang, Xue-feng, Zhao, Shuang, Wu, Ya-zhou, Takano, Yasuo, Sun, Hong-zhi, Su, Rong-jian, Luo, Jun-sheng, Gou, Wen-feng
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637314/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637314/

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