CD44 enhances tumor aggressiveness by promoting tumor cell plasticity

CD44 enhances tumor aggressiveness by promoting tumor cell plasticity

Aggressive tumor cells can obtain the ability to transdifferentiate into cells with endothelial features and thus form vasculogenic networks. This phenomenon, called vasculogenic mimicry (VM), is associated with increased tumor malignancy and poor clinical outcome. To identify novel key molecules im...

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Bibliographic Details
Main Authors: Paulis, Yvette W.J., Huijbers, Elisabeth J.M., van der Schaft, Daisy W.J., Soetekouw, Patricia M.M.B., Pauwels, Patrick, Tjan-Heijnen, Vivianne C.G., Griffioen, Arjan W.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637310/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637310/

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