Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby promoting metastasis, supporting angiogenesis and...

Full description

Bibliographic Details
Main Authors: Naidoo, Kerrilyn, Malindisa, Sibusiso T., Otgaar, Tyrone C., Bernert, Martin, Da Costa Dias, Bianca, Ferreira, Eloise, Reusch, Uwe, Knackmuss, Stefan, Little, Melvyn, Weiss, Stefan F. T., Letsolo, Boitelo T.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636255/