Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior

Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior

Individuals with Cornelia de Lange Syndrome (CdLS) display diverse developmental deficits, including slow growth, multiple limb and organ abnormalities, and intellectual disabilities. Severely-affected individuals most often have dominant loss-of-function mutations in the Nipped-B-Like (NIPBL) gene,...

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Bibliographic Details
Main Authors: Wu, Yaning, Gause, Maria, Xu, Dongbin, Misulovin, Ziva, Schaaf, Cheri A., Mosarla, Ramya C., Mannino, Elizabeth, Shannon, Megan, Jones, Emily, Shi, Mi, Chen, Wen-Feng, Katz, Olivia L., Sehgal, Amita, Jongens, Thomas A., Krantz, Ian D., Dorsett, Dale
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636142/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636142/

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