Engineered biosynthesis of enduracidin lipoglycopeptide antibiotics using the ramoplanin mannosyltransferase Ram29

Engineered biosynthesis of enduracidin lipoglycopeptide antibiotics using the ramoplanin mannosyltransferase Ram29

The lipopeptides ramoplanin from Actinoplanes sp. ATCC 33076 and enduracidin produced by Streptomyces fungicidicus are effective antibiotics against a number of drug-resistant Gram-positive pathogens. While these two antibiotics share a similar cyclic peptide structure, comprising 17 amino acids wit...

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Bibliographic Details
Main Authors: Wu, Ming-Cheng, Styles, Matthew Q., Law, Brian J. C., Struck, Anna-Winona, Nunns, Laura, Micklefield, Jason
Format: Online
Language:English
Published: Society for General Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635501/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635501/

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