Non-linear leak currents affect mammalian neuron physiology

In their seminal works on squid giant axons, Hodgkin, and Huxley approximated the membrane leak current as Ohmic, i.e., linear, since in their preparation, sub-threshold current rectification due to the influence of ionic concentration is negligible. Most studies on mammalian neurons have made the s...

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Bibliographic Details
Main Authors: Huang, Shiwei, Hong, Sungho, De Schutter, Erik
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635211/