Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

Metabolic disorders, like diabetes and obesity, are pathogenic outcomes of imbalance in glucose metabolism. Nutrient excess and mitochondrial imbalance are implicated in dysfunctional glucose metabolism with age. We used conplastic mouse strains with defined mitochondrial DNA (mtDNA) mutations on a...

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Bibliographic Details
Main Authors: Chauhan, Anuradha, Weiss, Heike, Koch, Franziska, Ibrahim, Saleh M., Vera, Julio, Wolkenhauer, Olaf, Tiedge, Markus
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634931/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634931/

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