Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin

Necrotizing autoimmune myopathy (NAM) is a group of acquired myopathies characterized by prominent myofiber necrosis with little or no muscle inflammation. Recently, researchers identified autoantibodies (aAb) against 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) in patients with NAM, espe...

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Main Authors: Allenbach, Yves, Drouot, Laurent, Rigolet, Aude, Charuel, Jean Luc, Jouen, Fabienne, Romero, Norma B., Maisonobe, Thierry, Dubourg, Odile, Behin, Anthony, Laforet, Pascal, Stojkovic, Tania, Eymard, Bruno, Costedoat-Chalumeau, Nathalie, Campana-Salort, Emmanuelle, Tournadre, Anne, Musset, Lucile, Bader-Meunier, Brigitte, Kone-Paut, Isabelle, Sibilia, Jean, Servais, Laurent, Fain, Olivier, Larroche, Claire, Diot, Elisabeth, Terrier, Benjamin, De Paz, Raphael, Dossier, Antoine, Menard, Dominique, Morati, Chafika, Roux, Marielle, Ferrer, Xavier, Martinet, Jeremie, Besnard, Sophie, Bellance, Remi, Cacoub, Patrice, Arnaud, Laurent, Grosbois, Bernard, Herson, Serge, Boyer, Olivier, Benveniste, Olivier
Format: Online
Language:English
Published: Lippincott Williams & Wilkins 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632910/
id pubmed-4632910
recordtype oai_dc
spelling pubmed-46329102015-11-12 Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin Allenbach, Yves Drouot, Laurent Rigolet, Aude Charuel, Jean Luc Jouen, Fabienne Romero, Norma B. Maisonobe, Thierry Dubourg, Odile Behin, Anthony Laforet, Pascal Stojkovic, Tania Eymard, Bruno Costedoat-Chalumeau, Nathalie Campana-Salort, Emmanuelle Tournadre, Anne Musset, Lucile Bader-Meunier, Brigitte Kone-Paut, Isabelle Sibilia, Jean Servais, Laurent Fain, Olivier Larroche, Claire Diot, Elisabeth Terrier, Benjamin De Paz, Raphael Dossier, Antoine Menard, Dominique Morati, Chafika Roux, Marielle Ferrer, Xavier Martinet, Jeremie Besnard, Sophie Bellance, Remi Cacoub, Patrice Arnaud, Laurent Grosbois, Bernard Herson, Serge Boyer, Olivier Benveniste, Olivier Original Study Necrotizing autoimmune myopathy (NAM) is a group of acquired myopathies characterized by prominent myofiber necrosis with little or no muscle inflammation. Recently, researchers identified autoantibodies (aAb) against 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) in patients with NAM, especially in statin-exposed patients. Here we report what is to our knowledge the first European cohort of patients with NAM. Lippincott Williams & Wilkins 2014-05-06 /pmc/articles/PMC4632910/ /pubmed/24797170 http://dx.doi.org/10.1097/MD.0000000000000028 Text en Copyright © 2014 by Lippincott Williams & Wilkins
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Allenbach, Yves
Drouot, Laurent
Rigolet, Aude
Charuel, Jean Luc
Jouen, Fabienne
Romero, Norma B.
Maisonobe, Thierry
Dubourg, Odile
Behin, Anthony
Laforet, Pascal
Stojkovic, Tania
Eymard, Bruno
Costedoat-Chalumeau, Nathalie
Campana-Salort, Emmanuelle
Tournadre, Anne
Musset, Lucile
Bader-Meunier, Brigitte
Kone-Paut, Isabelle
Sibilia, Jean
Servais, Laurent
Fain, Olivier
Larroche, Claire
Diot, Elisabeth
Terrier, Benjamin
De Paz, Raphael
Dossier, Antoine
Menard, Dominique
Morati, Chafika
Roux, Marielle
Ferrer, Xavier
Martinet, Jeremie
Besnard, Sophie
Bellance, Remi
Cacoub, Patrice
Arnaud, Laurent
Grosbois, Bernard
Herson, Serge
Boyer, Olivier
Benveniste, Olivier
spellingShingle Allenbach, Yves
Drouot, Laurent
Rigolet, Aude
Charuel, Jean Luc
Jouen, Fabienne
Romero, Norma B.
Maisonobe, Thierry
Dubourg, Odile
Behin, Anthony
Laforet, Pascal
Stojkovic, Tania
Eymard, Bruno
Costedoat-Chalumeau, Nathalie
Campana-Salort, Emmanuelle
Tournadre, Anne
Musset, Lucile
Bader-Meunier, Brigitte
Kone-Paut, Isabelle
Sibilia, Jean
Servais, Laurent
Fain, Olivier
Larroche, Claire
Diot, Elisabeth
Terrier, Benjamin
De Paz, Raphael
Dossier, Antoine
Menard, Dominique
Morati, Chafika
Roux, Marielle
Ferrer, Xavier
Martinet, Jeremie
Besnard, Sophie
Bellance, Remi
Cacoub, Patrice
Arnaud, Laurent
Grosbois, Bernard
Herson, Serge
Boyer, Olivier
Benveniste, Olivier
Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
author_facet Allenbach, Yves
Drouot, Laurent
Rigolet, Aude
Charuel, Jean Luc
Jouen, Fabienne
Romero, Norma B.
Maisonobe, Thierry
Dubourg, Odile
Behin, Anthony
Laforet, Pascal
Stojkovic, Tania
Eymard, Bruno
Costedoat-Chalumeau, Nathalie
Campana-Salort, Emmanuelle
Tournadre, Anne
Musset, Lucile
Bader-Meunier, Brigitte
Kone-Paut, Isabelle
Sibilia, Jean
Servais, Laurent
Fain, Olivier
Larroche, Claire
Diot, Elisabeth
Terrier, Benjamin
De Paz, Raphael
Dossier, Antoine
Menard, Dominique
Morati, Chafika
Roux, Marielle
Ferrer, Xavier
Martinet, Jeremie
Besnard, Sophie
Bellance, Remi
Cacoub, Patrice
Arnaud, Laurent
Grosbois, Bernard
Herson, Serge
Boyer, Olivier
Benveniste, Olivier
author_sort Allenbach, Yves
title Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
title_short Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
title_full Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
title_fullStr Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
title_full_unstemmed Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
title_sort anti-hmgcr autoantibodies in european patients with autoimmune necrotizing myopathies: inconstant exposure to statin
description Necrotizing autoimmune myopathy (NAM) is a group of acquired myopathies characterized by prominent myofiber necrosis with little or no muscle inflammation. Recently, researchers identified autoantibodies (aAb) against 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) in patients with NAM, especially in statin-exposed patients. Here we report what is to our knowledge the first European cohort of patients with NAM.
publisher Lippincott Williams & Wilkins
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632910/
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