Secreted Frizzled-Related Protein Promotes Bone Regeneration by Human Bone Marrow-Derived Mesenchymal Stem Cells
Secreted frizzled-related protein (sFRP)-3 is a negative regulator of Wnt signaling in human mesenchymal stem cells (hMSCs). The present study investigated the effects sFRP-3 on osteogenic differentiation by assessing osteogenic gene expression in hMSCs in vitro and by examining bone regeneration in...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632696/ |