Requirements within the Ebola Viral Glycoprotein for Tetherin Antagonism

Tetherin is an interferon-induced, intrinsic cellular response factor that blocks release of numerous viruses, including Ebola virus, from infected cells. As with many viruses targeted by host factors, Ebola virus employs a tetherin antagonist, the viral glycoprotein (EboGP), to counteract restricti...

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Bibliographic Details
Main Authors: Vande Burgt, Nathan H., Kaletsky, Rachel L., Bates, Paul
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632396/